Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942460 | 0.92 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1TNFRSF1A | |
| SCHEMBL7933641 | 0.91 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL7943106 | 0.84 | HSPA5 (0.38) | ALDH1A1TSHRSMN1; SMN2CA1CA2 | |
| SCHEMBL8397544 | 0.81 | RARG (0.35) | ALDH1A1TSHRTDP1SMN1; SMN2DHFR | |
| SCHEMBL7940191 | 0.81 | HSPA5 (0.41) | ALDH1A1TSHRTDP1SMN1; SMN2DHFR | |
| SCHEMBL7933963 | 0.78 | ALDH1A1 (0.31) | ALDH1A1TSHRTDP1DHFR | |
| SCHEMBL7940306 | 0.78 | KMT2A (0.46) | ALDH1A1TSHR | |
| SCHEMBL7940053 | 0.77 | DHFR (0.40) | ALDH1A1TSHRTDP1TNFRSF1ASMN1; SMN2 | |
| SCHEMBL7940078 | 0.76 | HSPA5 (0.36) | ALDH1A1TSHRSMN1; SMN2CA1CA2 | |
| SCHEMBL8397543 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1SMN1; SMN2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |