SCHEMBL7933781

SCHEMBL7933781

CCC(O)(C(=O)O)c1ccc(O)c(C2(C)CCCCC2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.47
RARG P13631 4/20 0.47
RARA P10276 3/20 0.45
PTPN11 Q06124 1/20 0.41
PTGDR Q13258 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
ESR1 P03372 4/20 0.36
ESR2 Q92731 4/20 0.36
ADORA3 P0DMS8 1/20 0.35
AR P10275 2/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34
CYP26B1 Q9NR63 2/20 0.34
ERCC1 P07992 1/20 0.34
ERCC4 Q92889 1/20 0.34
CYP26A1 O43174 1/20 0.34
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933933 0.85 RARB (0.51) RARBRARGRARAPTGDRPTGDR2
SCHEMBL8594630 0.83 GLA (0.41) RARBRARGRARAPTPN11PTGDR
SCHEMBL8595052 0.82 GLA (0.43) RARBRARGRARAPTPN11PTGDR
SCHEMBL7933971 0.80 TSHR (0.36) RARBRARGRARAPTGDRPTGDR2
SCHEMBL7933908 0.77 PTGDR (0.36) RARBRARGRARAPTGDRPTGDR2
SCHEMBL9481839 0.76 ALDH1A1 (0.50) RARBRARGRARAPTPN11ESR1
SCHEMBL7942422 0.76 PTGDR (0.36) RARBRARGRARAPTGDRPTGDR2
SCHEMBL7940461 0.74 RARG (0.34) RARBRARGRARAPTGDRPTGDR2
SCHEMBL3838214 0.72 ESR1 (0.45) ESR1ESR2ARTSHR
SCHEMBL3809004 0.72 RARB (0.74) RARBRARGRARAPTPN11RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed