SCHEMBL7942422

SCHEMBL7942422

CCc1cc(C(O)(CC)C(=O)O)cc(C2(C)CCCCC2)c1OC

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGDR Q13258 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36
RARB P10826 4/20 0.35
RARG P13631 4/20 0.35
RARA P10276 3/20 0.35
ADORA3 P0DMS8 1/20 0.32
GLA P06280 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933908 0.89 PTGDR (0.36) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7940461 0.86 RARG (0.34) PTGDRPTGDR2RARBRARGRARA
SCHEMBL8595052 0.84 GLA (0.43) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7933933 0.80 RARB (0.51) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7786557 0.79 RARB (0.47) PTGDRPTGDR2RARBRARGRARA
SCHEMBL8594630 0.78 GLA (0.41) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7792167 0.77 PTGDR (0.43) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7933781 0.76 RARB (0.47) PTGDRPTGDR2RARBRARGRARA
SCHEMBL8400776 0.75 ALOX5 (0.43) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7796429 0.75 CYP26B1 (0.41) PTGDRPTGDR2RARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed