Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | F2R | P25116 | 2/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942551 | 0.95 | DHFR (0.38) | DHFRVCAM1PTGS2CYP3A4ALDH1A1 | |
| SCHEMBL7940053 | 0.89 | DHFR (0.40) | DHFRPTGS2CYP3A4ALDH1A1TDP1 | |
| SCHEMBL7941416 | 0.84 | ALDH1A1 (0.47) | VCAM1CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL8397543 | 0.84 | ALDH1A1 (0.35) | DHFRPTGS2CYP3A4ALDH1A1TDP1 | |
| SCHEMBL6566985 | 0.81 | TNKS2 (0.44) | DHFRVCAM1PTGS2CYP3A4ALDH1A1 | |
| SCHEMBL7941099 | 0.80 | ALDH1A1 (0.49) | VCAM1CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL7941240 | 0.79 | CYP1A2 (0.44) | VCAM1CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL7933641 | 0.79 | ALDH1A1 (0.35) | VCAM1CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL6568715 | 0.79 | TNKS2 (0.49) | DHFRVCAM1PTGS2CYP3A4ALDH1A1 | |
| SCHEMBL7933921 | 0.78 | ALDH1A1 (0.46) | CYP3A4ALDH1A1TDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5874494-A | DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |