Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931370 | 0.88 | CNR1 (0.51) | CNR1CREBBPPOLBL3MBTL1SRD5A1 | |
| SCHEMBL27537255 | 0.87 | SRD5A1 (0.49) | CNR1CREBBPSRD5A1SRD5A2CNR2 | |
| SCHEMBL7861333 | 0.83 | CNR1 (0.67) | CNR1CREBBPPOLBL3MBTL1SRD5A1 | |
| SCHEMBL7933927 | 0.83 | CNR1 (0.55) | CNR1CREBBPPOLBL3MBTL1SRD5A1 | |
| SCHEMBL7934794 | 0.81 | CNR1 (0.63) | CNR1CREBBPPOLBL3MBTL1SRD5A1 | |
| Hydrochloric Acid SCHEMBL7933289 | 0.80 | ADRA1D (0.45) | CNR1POLBALDH1A1TSHR | |
| SCHEMBL7859329 | 0.79 | CNR1 (0.56) | CNR1CREBBPPOLBL3MBTL1SRD5A1 | |
| SCHEMBL7853735 | 0.79 | CNR1 (0.70) | CNR1CREBBPPOLBL3MBTL1SRD5A1 | |
| SCHEMBL8793547 | 0.78 | CNR1 (0.73) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL27304797 | 0.76 | CNR1 (0.70) | CNR1CREBBPPOLBL3MBTL1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242449-B1 | TREATING PROSTATIC HYPERTROPHY, URINATION DISORDERS ASSOCIATED WITH PROSTATIC HYPERTROPHY, MALE PATTERN ALOPECIA, OR ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0997457-A1 | 3-BENZOYLINDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |