Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935980 | 0.87 | GAA (0.40) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7925330 | 0.82 | GAA (0.36) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7932049 | 0.79 | CYP1A2 (0.32) | CYP1A2CYP2C19 | |
| SCHEMBL7932057 | 0.68 | KMT2A (0.36) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7925284 | 0.67 | KMT2A (0.37) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7934698 | 0.65 | LRRK2 (0.35) | CYP1A2CYP2C19 | |
| SCHEMBL8873231 | 0.64 | LRRK2 (0.34) | GAAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL8873230 | 0.63 | LRRK2 (0.40) | CYP1A2CYP2C19 | |
| SCHEMBL3237315 | 0.63 | GAA (0.53) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4856408 | 0.62 | KMT2A (0.61) | GAACYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |