Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934698 | 0.86 | LRRK2 (0.35) | CYP1A2PDE4ACYP2C19LRRK2 | |
| SCHEMBL7925300 | 0.80 | LRRK2 (0.32) | CYP1A2PDE4ACYP2C19LRRK2 | |
| SCHEMBL8873230 | 0.80 | LRRK2 (0.40) | CYP1A2PDE4ACYP2C19LRRK2 | |
| SCHEMBL7933967 | 0.79 | GAA (0.34) | CYP1A2CYP2C19 | |
| SCHEMBL7925343 | 0.77 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL7932063 | 0.77 | KDM4E (0.31) | — | |
| SCHEMBL7937900 | 0.76 | LRRK2 (0.30) | LRRK2 | |
| SCHEMBL8873752 | 0.74 | LRRK2 (0.32) | LRRK2 | |
| SCHEMBL8873231 | 0.74 | LRRK2 (0.34) | PDE4ALRRK2 | |
| SCHEMBL8874150 | 0.66 | LRRK2 (0.34) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |