Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925300 | 0.89 | LRRK2 (0.32) | LRRK2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL8873230 | 0.89 | LRRK2 (0.40) | LRRK2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL7932049 | 0.86 | CYP1A2 (0.32) | LRRK2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL7925343 | 0.86 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL7937900 | 0.85 | LRRK2 (0.30) | LRRK2 | |
| SCHEMBL8873231 | 0.82 | LRRK2 (0.34) | LRRK2PDE4ALMNA | |
| SCHEMBL8873752 | 0.82 | LRRK2 (0.32) | LRRK2 | |
| SCHEMBL9192068 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL8874150 | 0.73 | LRRK2 (0.34) | LRRK2 | |
| SCHEMBL7934006 | 0.72 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |