Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528963 | 1.00 | ALDH1A1 (0.43) | ALDH1A1AKR1C2AKR1C1CRHBPCRHR2 | |
| SCHEMBL345864 | 1.00 | ALDH1A1 (0.43) | ALDH1A1AKR1C2AKR1C1CRHBPCRHR2 | |
| SCHEMBL10411118 | 0.98 | ALDH1A1 (0.41) | ALDH1A1AKR1C2AKR1C1CRHBPCRHR2 | |
| SCHEMBL30612486 | 0.98 | ALDH1A1 (0.38) | ALDH1A1AKR1C2AKR1C1CRHBPCRHR2 | |
| SCHEMBL596786 | 0.93 | ALDH1A1 (0.50) | ALDH1A1CRHBPCRHR2MAOAALOX5 | |
| SCHEMBL10624682 | 0.91 | ALDH1A1 (0.43) | ALDH1A1AKR1C2AKR1C1CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL9574779 | 0.90 | ALDH1A1 (0.47) | ALDH1A1CRHBPCRHR2MAOAALOX5 | |
| Iodide SCHEMBL7170134 | 0.90 | ALDH1A1 (0.47) | ALDH1A1CRHBPCRHR2MAOAALOX5 | |
| SCHEMBL29968018 | 0.90 | ALDH1A1 (0.47) | ALDH1A1CRHBPCRHR2MAOAKIF11 | |
| SCHEMBL12266121 | 0.90 | ALDH1A1 (0.47) | ALDH1A1CRHBPCRHR2MAOAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906261-B1 | HYDROFORMYLATION PROCESS AND CATALYSTS SUITABLE THEREFOR CONTAINING PHOSPHORUS COMPOUNDS AS LIGANDS | BASF AG (DE) | 2001-05-09 | — | — | EP | disclosed |