Sugi Predict

Sugi Predict / Compounds / SCHEMBL345864

SCHEMBL345864

SCHEMBL345864

F[B-](F)(F)F.c1ccc(-c2cc(-c3ccccc3)[o+]c(-c3ccccc3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.43
▸ AKR1C2 P52895 3/20 0.37
▸ AKR1C1 Q04828 3/20 0.37
▸ CRHBP P24387 1/20 0.37
▸ CRHR2 Q13324 1/20 0.37
▸ MAOA P21397 1/20 0.34
▸ KIF11 P52732 1/20 0.34
▸ PTPN1 P18031 3/20 0.34
▸ PTPN5 P54829 2/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ AKR1C4 P17516 1/20 0.33
▸ AKR1C3 P42330 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ TAAR1 Q96RJ0 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ NOTUM Q6P988 1/20 0.33
▸ MMP3 P08254 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528963 1.00 ALDH1A1 (0.43) ALDH1A1AKR1C2AKR1C1CRHBPCRHR2
SCHEMBL7933978 1.00 ALDH1A1 (0.43) ALDH1A1AKR1C2AKR1C1CRHBPCRHR2
SCHEMBL10411118 0.98 ALDH1A1 (0.41) ALDH1A1AKR1C2AKR1C1CRHBPCRHR2
SCHEMBL30612486 0.98 ALDH1A1 (0.38) ALDH1A1AKR1C2AKR1C1CRHBPCRHR2
SCHEMBL596786 0.93 ALDH1A1 (0.50) ALDH1A1CRHBPCRHR2MAOAALOX5
SCHEMBL10624682 0.91 ALDH1A1 (0.43) ALDH1A1AKR1C2AKR1C1CRHBPCRHR2
Hydrochloric Acid SCHEMBL9574779 0.90 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAALOX5
Iodide SCHEMBL7170134 0.90 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAALOX5
SCHEMBL29968018 0.90 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAKIF11
SCHEMBL12266121 0.90 ALDH1A1 (0.47) ALDH1A1CRHBPCRHR2MAOAKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178692-B Composite material for virus preservation tube and preparation method thereof 深圳市远景医疗器械模具有限公司 2024-10-18 — — CN claimed
EP-4392426-A1 SOLID FORMS OF SPIROTRICYCLIC APOL1 INHIBITORS AND METHODS OF USING SAME Vertex Pharmaceuticals Incorporated (US) 2024-07-03 — — EP claimed
CN-118103379-A Solid forms of spirocyclic APOL1 inhibitors and methods of use thereof 弗特克斯药品有限公司 2024-05-28 — — CN claimed
CN-115012211-B Antibacterial anti-ultraviolet cotton fabric and preparation method thereof 南通大学 2023-08-08 — — CN claimed
CN-116178692-A Composite material for virus preservation tube and preparation method thereof 深圳市远景医疗器械模具有限公司 2023-05-30 — — CN claimed
CN-114524815-B 8-alkoxypurine derivative and preparation method and application thereof 华南理工大学 2023-05-23 — — CN claimed
WO-2023028237-A1 SOLID FORMS OF SPIROTRICYCLIC APOL1 INHIBITORS AND METHODS OF USING SAME VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-03-02 — — WO claimed
CN-115716828-A Synthesis method of pyrazolo [1,5-a ] pyridine compound 华南理工大学 2023-02-28 — — CN claimed
CN-114059235-B Photoresponse polyurethane conductive nanofiber membrane and preparation method thereof 南京摩开科技有限公司 2022-12-02 — — CN claimed
CN-115012211-A Antibacterial ultraviolet-proof cotton fabric and preparation method thereof 南通大学 2022-09-06 — — CN claimed
CN-114059235-A Photoresponse polyurethane conductive nanofiber membrane and preparation method thereof 南京摩开科技有限公司 2022-02-18 — — CN claimed
US-20200108381-A1 Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2020-04-09 — — US claimed
US-6734221-B1 A PHOTOINITIATED RADICAL GENERATING COMPONENT AND A PHOTOINITIATOR COMPONENT LOCTITE (R&D) LIMITED (IE) 2004-05-11 — — US claimed
WO-2001018068-A9 RADIATION-CURABLE, CYANOACRYLATE-CONTAINING COMPOSITIONS LOCTITE CORP (US) 2002-10-03 — — WO claimed
EP-0626431-B1 PHOTOCURABLE CONDUCTIVE COATING COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2000-01-26 — — EP claimed
US-5429846-A Antimony oxide-containing tin oxide powder, (meth) acrylate compound, acetal resin, photopolymerization initiator and organic solvent SEKISUI CHEMICAL CO., LTD. (JP) 1995-07-04 — — US claimed
EP-0626431-A1 PHOTOCURABLE CONDUCTIVE COATING COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 1994-11-30 — — EP claimed
EP-0196561-B1 PHOTOSENSITIVE LITHOGRAPHIC PRINTING PLATE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-06-14 — — EP claimed
EP-0196561-A1 Photosensitive lithographic printing plate NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-10-08 — — EP claimed
US-4105447-A Photoconductive insulating compositions including polyaryl hydrocarbon photoconductors EASTMAN KODAK COMPANY (US) 1978-08-08 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200108381-A1 Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis PPOX, CYBA, CYBB ALDH1A1 1395/4885AKR1C2 1360/4885AKR1C1 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.