SCHEMBL7934032

SCHEMBL7934032

CCCCCCCCc1cc([N+](=O)[O-])[c]c([N+](=O)[O-])c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.46
PTGS2 P35354 4/20 0.46
KCNH2 Q12809 1/20 0.46
CYP3A4 P08684 2/20 0.43
FUT7 Q11130 1/20 0.43
ALDH1A1 P00352 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10497050 0.81 KCNH2 (0.45) GPR84PTGS2KCNH2CYP3A4ALDH1A1
SCHEMBL3794045 0.81 KCNH2 (0.45) GPR84PTGS2KCNH2CYP3A4ALDH1A1
SCHEMBL19829355 0.79 KCNH2 (0.55) GPR84PTGS2KCNH2CYP3A4FUT7
SCHEMBL4928170 0.78 KCNH2 (0.42) KCNH2ALDH1A1
SCHEMBL11206702 0.75 ESR1 (0.57) GPR84PTGS2CYP3A4FUT7ESR1
SCHEMBL1861075 0.75 ESR1 (0.57) GPR84PTGS2CYP3A4FUT7ESR1
SCHEMBL8733612 0.75 ESR1 (0.57) GPR84PTGS2CYP3A4FUT7ESR1
SCHEMBL11204852 0.75 ESR1 (0.57) GPR84PTGS2CYP3A4FUT7ESR1
SCHEMBL3794039 0.72 KCNH2 (0.40) GPR84KCNH2ALDH1A1
SCHEMBL7628223 0.72 PTGS2 (0.70) GPR84PTGS2CYP3A4FUT7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693254-B1 Gel formulations containing insecticides for vaporizer systems BAYER AG (DE) 2001-10-24 EP disclosed
US-5645845-A CONTAINING PYRETHROID-TYPE COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1997-07-08 US disclosed
EP-0693254-A1 Gel formulations containing insecticides for vaporizer systems BAYER AG (DE) 1996-01-24 EP disclosed
US-4663315-A Device and method for vaporizing thermally vaporizable composition EARTH CHEMICAL COMPANY, LIMITED (JP) 1987-05-05 US disclosed