Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497050 | 1.00 | KCNH2 (0.45) | KCNH2KAT8PPARAGPR84LPL | |
| SCHEMBL9653209 | 0.87 | ALOX5 (0.38) | KCNH2KDM4EALDH1A1 | |
| SCHEMBL7934032 | 0.81 | GPR84 (0.46) | KCNH2GPR84PTGS2ESR1ADRA2A | |
| SCHEMBL457530 | 0.80 | KAT2B (0.36) | PTGS2ALDH1A1LMNA | |
| SCHEMBL27357221 | 0.78 | TDP1 (0.32) | — | |
| SCHEMBL10746021 | 0.78 | TAAR1 (0.35) | ADRA2ASLC6A2SLC6A3KDM4EALDH1A1 | |
| SCHEMBL9321110 | 0.77 | TXNRD1 (0.44) | KCNH2ALDH1A1CYP3A4 | |
| SCHEMBL8179540 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL9320496 | 0.75 | CYSLTR2 (0.38) | GPR84ESR1LMNA | |
| SCHEMBL15067037 | 0.75 | PTGS2 (0.46) | KAT8PPARALPLLIPGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027514-A2 | COATED SENSORS AND METHODS RELATED THERETO | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| WO-2009051703-A1 | ION-SELECTIVE SENSORS | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| EP-2049900-A2 | QUANTUM DOT BASED FLUORESCENT ION-SENSOR | The Charles Stark Draper Laboratory, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008016646-A2 | QUANTUM DOT BASED FLUORESCENT ION-SENSOR | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2008-02-07 | — | — | WO | disclosed |
| EP-0619019-A4 | ANALYTE AND PH MEASURING SENSOR ASSEMBLY AND METHOD. | PPG INDUSTRIES INC (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0619019-A1 | ANALYTE AND pH MEASURING SENSOR ASSEMBLY AND METHOD | PPG INDUSTRIES, INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5336388-A | Computerized electrochemical sensor; miniaturization, accuracy; medical analyzing | PPG INDUSTRIES, INC. (US) | 1994-08-09 | — | — | US | disclosed |
| WO-1993013411-A1 | ANALYTE AND pH MEASURING SENSOR ASSEMBLY AND METHOD | PPG INDUSTRIES, INC. (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4454007-A | CARBON DISPERSED IN A DIELECTRIC POLYMER, PARTIALLYL INTERDIFFUSED WITH MEMBRANE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |