SCHEMBL7934034

SCHEMBL7934034

COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(F)cc(OC(F)(F)F)n1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
NPC1 O15118 2/20 0.42
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
CDK1 P06493 1/20 0.39
PTPN2 P17706 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPN5 P54829 1/20 0.39
SLC40A1 Q9NP59 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3500652 0.94 GAA (0.48) GAANPC1MAPTMEN1KMT2A
SCHEMBL7932024 0.91 GAA (0.53) GAANPC1MAPTMEN1KMT2A
SCHEMBL9364617 0.90 GAA (0.59) GAANPC1MAPTMEN1KMT2A
SCHEMBL8873592 0.85 GAA (0.46) GAANPC1MAPTCDK1KDM4E
SCHEMBL10645916 0.84 GAA (0.53) GAANPC1MAPTMEN1KMT2A
SCHEMBL8872701 0.84 GAA (0.45) GAANPC1MAPTMEN1KMT2A
SCHEMBL10645399 0.83 GAA (0.42) GAANPC1MAPTMEN1KMT2A
SCHEMBL28433647 0.83 GAA (0.45) GAANPC1MAPTMEN1KMT2A
SCHEMBL1405765 0.82 GAA (0.59) GAANPC1MAPTMEN1KMT2A
SCHEMBL9197338 0.82 MAPT (0.43) GAANPC1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235904-B1 VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed
US-5283332-A 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1994-02-01 US disclosed
US-5276007-A Herbicidal sulfonylureas BASF AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed
US-5237063-A TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed