SCHEMBL7934049

SCHEMBL7934049

CCc1ccccc1C1=C(c2ccccc2CC)CC=C1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
MGLL Q99685 1/20 0.34
CYP2D6 P10635 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
CSNK2A3 Q8NEV1 1/20 0.34
LMNA P02545 3/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
TSHR P16473 1/20 0.32
SLC9A1 P19634 1/20 0.31
PDK2 Q15119 1/20 0.30
CTSB P07858 1/20 0.30
DHFR P00374 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7567521 0.78 CSNK2A2 (0.32) TRPA1MGLLCYP2D6CSNK2A2CSNK2B
Hydrochloric Acid SCHEMBL7567523 0.78 CYP2D6 (0.35) TRPA1MGLLCYP2D6CSNK2A2CSNK2B
SCHEMBL198461 0.71 CSNK2A2 (0.52) TRPA1MGLLCYP2D6CSNK2A2CSNK2B
SCHEMBL5344338 0.69 CYP2D6 (0.36) MGLLCYP2D6CSNK2A2CSNK2BCSNK2A1
SCHEMBL11382359 0.69 CSNK2A2 (0.50) TRPA1MGLLCYP2D6CSNK2A2CSNK2B
Ethane SCHEMBL3687850 0.69 CSNK2A2 (0.50) TRPA1MGLLCYP2D6CSNK2A2CSNK2B
SCHEMBL2776956 0.69 CSNK2A2 (0.50) TRPA1MGLLCYP2D6CSNK2A2CSNK2B
SCHEMBL3980393 0.68 MAOA (0.43) CYP2D6LMNAMAPTTSHRNPC1
SCHEMBL28654786 0.67 ALDH1A1 (0.43) LMNAMAPTL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL3209410 0.67 PDCD1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232516-B1 Process for cyclopentadiene substitution DSM N.V. (NL) 2001-05-15 US disclosed