SCHEMBL7934307

SCHEMBL7934307

O=C(CCCCCC(=O)c1ccc(C(=O)O)c(C(=O)O)c1)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
CDC25A P30304 1/20 0.52
CDC25B P30305 1/20 0.52
HSD17B10 Q99714 1/20 0.52
POLB P06746 1/20 0.50
HDAC1 Q13547 7/20 0.48
HDAC8 Q9BY41 6/20 0.48
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31186552 0.90 HSD17B10 (0.57) L3MBTL1TDP1LMNACDC25ACDC25B
SCHEMBL8962350 0.83 HPGD (0.54) L3MBTL1TDP1MAPTCDC25ACDC25B
SCHEMBL5265466 0.82 L3MBTL1 (0.40) L3MBTL1TDP1LMNAMAPTCDC25A
SCHEMBL10657009 0.81 HDAC3 (0.54) L3MBTL1TDP1LMNAMAPTHSD17B10
Adipic Acid SCHEMBL4371438 0.81 KDM4E (0.55) L3MBTL1TDP1LMNAMAPTCDC25A
SCHEMBL28484657 0.80 HSD17B3 (0.53) HSD17B3
Adipic Acid SCHEMBL10713644 0.79 KDM4E (0.53) L3MBTL1TDP1LMNAMAPTCDC25A
SCHEMBL27807893 0.79 KDM4E (0.67) L3MBTL1TDP1LMNAMAPTCDC25A
SCHEMBL2996893 0.79 PPARA (0.60) MAPTKDM4EHSD17B3
SCHEMBL10595067 0.79 KAT8 (0.60) MAPTHSD17B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268460-B1 POLYIMIDES, POLYAMIC ACID AND ESTER COPOLYMERS GIBBONS WAYNE M (US) 2001-07-31 US disclosed
US-6242061-B1 POLYAMIC ACIDS, POLYIMIDES ELSICON INC. 2001-06-05 US disclosed
US-6143380-A POLYIMIDES ELSICON INC. (US) 2000-11-07 US disclosed