SCHEMBL8962350

SCHEMBL8962350

CCCC(=O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.54
HSD17B3 P37058 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 2/20 0.50
CDC25A P30304 1/20 0.50
CDC25B P30305 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
POLB P06746 1/20 0.49
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 4/20 0.44
RAB9A P51151 3/20 0.44
MAPT P10636 2/20 0.44
NPC1 O15118 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31186552 0.88 HSD17B10 (0.57) HPGDL3MBTL1SMN1; SMN2HSD17B10CDC25A
SCHEMBL5326647 0.86 HSD17B3 (0.55) HPGDHSD17B3L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL8962217 0.85 CDC25A (0.53) HPGDL3MBTL1SMN1; SMN2HSD17B10CDC25A
SCHEMBL10807141 0.84 ALDH1A1 (0.50) HPGDHSD17B3L3MBTL1SMN1; SMN2HSD17B10
Butyric Acid SCHEMBL121030 0.84 KDM4E (0.51) HPGDL3MBTL1HSD17B10CDC25ACDC25B
SCHEMBL7934307 0.83 L3MBTL1 (0.53) HSD17B3L3MBTL1HSD17B10CDC25ACDC25B
SCHEMBL11620041 0.83 HPGD (0.47) HPGDHSD17B3L3MBTL1SMN1; SMN2HSD17B10
Terephthalic Acid SCHEMBL7237482 0.82 KDM4E (0.50) L3MBTL1HSD17B10CDC25ACDC25BTDP1
SCHEMBL5325908 0.82 CTNNB1 (0.55) HPGDHSD17B3L3MBTL1SMN1; SMN2KDM4E
Butyric Acid SCHEMBL27742018 0.81 KDM4E (0.49) HPGDL3MBTL1HSD17B10CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5530130-A DYEING PLASTICS BAYER AKTIENGESELLSCHAFT (DE) 1996-06-25 US disclosed
EP-0639624-A1 Phthaloperinone dyestuffs BAYER AG (DE) 1995-02-22 EP disclosed