Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RGS4 | P49798 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435608 | 0.90 | NR1H2 (0.39) | PTGS1PTGS2RGS4MGLLDRD3 | |
| SCHEMBL7930835 | 0.89 | NR1H2 (0.44) | PTGS1PTGS2RGS4MGLLNR1H2 | |
| SCHEMBL7932654 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 | |
| SCHEMBL7936995 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 | |
| SCHEMBL7934341 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 | |
| SCHEMBL7933380 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 | |
| SCHEMBL7933400 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 | |
| SCHEMBL7932652 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 | |
| SCHEMBL7933454 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 | |
| SCHEMBL7930947 | 0.88 | NR1H2 (0.47) | PTGS1PTGS2MGLLNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174989-B1 | SYNTHETIC RUBBERS AND VULCANIZATION FOR TIRES | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-01-16 | — | — | US | disclosed |
| US-5981662-A | VULCANIZATES FOR USE IN SIDEWALL, TREAD, CARCASS PLY, WIRECOAT OR OVERLAY COMPOUNDS FOR TIRES; IMPART ANTI-REVERSION AND ANTIFATIGUE PROPERTIES IN THE RUBBER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0908489-A2 | Rubber compounds containing polymeric bis-succinimide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |