SCHEMBL7934396

SCHEMBL7934396

C=C(N[C@H](C(=O)N1C[C@@H](O)C[C@H]1C(=O)OC)C(C)(C)C)OC1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
MMP2 P08253 2/20 0.36
ANPEP P15144 2/20 0.36
PEPD P12955 1/20 0.34
VHL P40337 5/20 0.34
ELOC Q15369 4/20 0.34
ELOB Q15370 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11947498 0.89 ALDH1A1 (0.48) ALDH1A1MMP2ANPEP
SCHEMBL1166871 0.89 ALDH1A1 (0.48) ALDH1A1MMP2ANPEP
SCHEMBL8062037 0.89 ALDH1A1 (0.48) ALDH1A1MMP2ANPEP
SCHEMBL28577731 0.81 MMP2 (0.47) ALDH1A1MMP2ANPEPPEPDVHL
SCHEMBL12772463 0.79 ALDH1A1 (0.45) ALDH1A1MMP2ANPEPPEPDVHL
SCHEMBL8274197 0.79 ATM (0.45)
SCHEMBL11947497 0.79 ATM (0.45)
SCHEMBL8275235 0.79 ATM (0.45)
SCHEMBL8273040 0.78 ELANE (0.36)
SCHEMBL8272849 0.78 ELANE (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010033444-A1 CRYSTALLINE FORMS OF A 2-THIAZOLYL- 4-QUINOLINYL-OXY DERIVATIVE, A POTENT HCV INHIBITOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-03-25 WO disclosed