Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GPR39 | O43194 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934055 | 0.89 | IDH2 (0.34) | CYP1A2CYP2C19PDE4APOLBMAPT | |
| SCHEMBL7934015 | 0.88 | PGK1 (0.35) | CYP1A2CYP2C19PDE4APOLBMAPT | |
| SCHEMBL7798127 | 0.83 | ADORA1 (0.32) | CYP1A2CYP2C19PDE4APOLBIDH2 | |
| SCHEMBL8873226 | 0.83 | MAPT (0.34) | CYP1A2CYP2C19PDE4AMAPTIDH2 | |
| SCHEMBL7805860 | 0.83 | CYP1A2 (0.42) | CYP1A2MAPTKDM4ELMNA | |
| SCHEMBL7932041 | 0.81 | KDM4E (0.44) | CYP1A2CYP2C19POLBMAPTIDH2 | |
| SCHEMBL8873740 | 0.79 | SMN1; SMN2 (0.38) | CYP1A2CYP2C19PDE4AKDM4EATM | |
| SCHEMBL7804825 | 0.79 | NUDT1 (0.36) | — | |
| SCHEMBL12963409 | 0.78 | CYP1A2 (0.47) | CYP1A2KDM4ELMNA | |
| SCHEMBL9194620 | 0.78 | ATF1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |