SCHEMBL7934787

SCHEMBL7934787

C=CC(=O)OCCC(O)(CCOC(=O)C=C)CN=C=O

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
ALDH1A1 P00352 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 1/20 0.43
HPGD P15428 1/20 0.40
THRB P10828 2/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124929 0.75 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL23633199 0.75 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4832680 0.75 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4399491 0.74 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29151968 0.74 ALDH1A1 (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21409480 0.74 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29547475 0.74 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29871291 0.73 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL321508 0.73 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21861375 0.72 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115004083-B Head-up display system 日本化药株式会社 2025-03-11 CN disclosed
CN-114868048-B Optical film, optical laminate, functional glass, and head-up display 日本化药株式会社 2025-02-25 CN disclosed
CN-116997831-A Optical functional film for head-up display, optical laminate, functional glass, and head-up display system 日本化药株式会社 2023-11-03 CN disclosed
US-6306502-B1 COMPOSITION COMPRISING ULTRAVIOLET-CURABLE SILICONE, MONOMER MIXTURE COMPRISING TRIS((METH)ACRYLOYLOXYALKYL)ISOCYANURATE AND URETHANE POLY(METH)ACRYLATE HAVING ALICYCLIC SKELETON, PHOTOPOLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 2001-10-23 US disclosed
EP-0869154-A1 COATING COMPOSITION FORMING WEAR-RESISTANT COAT AND ARTICLE COVERED WITH THE COAT MITSUBISHI RAYON CO., LTD. (JP) 1998-10-07 EP disclosed