SCHEMBL321508

SCHEMBL321508

C=CC(=O)OCCCN=C=O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 1/20 0.53
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321389 0.95 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5358883 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5358179 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5350736 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1854743 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321467 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10599659 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1701307 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL22609056 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21019102 0.90 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES BAUSCH & LOMB IRELAND LTD (IE) 2026-03-19 US claimed
WO-2025215096-A1 SILICONE CONTACT LENS-FORMING PREPOLYMER AND SILICONE CONTACT LENS FORMED THEREFROM BAUSCH + LOMB IRELAND LIMITED (IE) 2025-10-16 WO claimed
EP-4543954-A1 LOW VISCOSITY ASPARTATE TERMINATED PREPOLYMERS FOR ADHESIVE APPLICATIONS Covestro LLC (US) 2025-04-30 EP claimed
CN-119256031-A Low viscosity aspartate-terminated prepolymers for adhesive applications 科思创有限公司 2025-01-03 CN claimed
WO-2024217872-A1 RIGID GAS PERMEABLE PREPOLYMER AND RIGID GAS PERMEABLE CONTACT LENS FORMED THEREFROM BAUSCH + LOMB IRELAND LIMITED (IE) 2024-10-24 WO claimed
US-20240352170-A1 RIGID GAS PERMEABLE PREPOLYMER AND RIGID GAS PERMEABLE CONTACT LENS FORMED THEREFROM JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-10-24 US claimed
CN-117343563-B Bio-based polyacrylate dispersion and preparation method and application thereof 江门瓦铂新材料有限公司 2024-07-02 CN claimed
CN-117567979-B High-temperature-resistant reversible self-repairing UV and moisture dual-curing three-proofing adhesive 信泰永合(烟台)新材料有限公司 2024-05-28 CN claimed
CN-117343249-B Organosilicon modified photo-curing bio-based polyacrylate dispersion, and preparation method and application thereof 江门瓦铂新材料有限公司 2024-05-28 CN claimed
CN-117567979-A High-temperature-resistant reversible self-repairing UV and moisture dual-curing three-proofing adhesive 信泰永合(烟台)新材料有限公司 2024-02-20 CN claimed
CN-101970550-A Polymer carbon nanotube composites NANOLEDGE INC 2011-02-09 CN claimed
CN-101589091-A Synthesis of cationic silicone prepolymers BAUSCH & LOMB (US) 2009-11-25 CN claimed
CN-101547955-A Polymerizable monomer composition and method for preventing polymerization SHOWA DENKO KK (JP) 2009-09-30 CN claimed
EP-2091994-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION Showa Denko K.K. (JP) 2009-08-26 EP claimed
WO-2008069256-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION SHOWA DENKO K.K. (JP) 2008-06-12 WO claimed
EP-0523723-B1 Resin composition MITSUI TOATSU CHEMICALS (JP) 1997-11-05 EP claimed
US-5418288-A Acrylic graft polymers with isocyanate group MITSUI TOATSU CHEMICALS, INC. (JP) 1995-05-23 US claimed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US claimed
EP-0523723-A1 Resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP claimed
US-5010155-A Hydrophilic film CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES CRYAA, CRYAB, CRYZ TSHR 553/4885ALDH1A1 2751/4885CYP3A4 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.