Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyl Alcohol SCHEMBL30712613 | 1.00 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL27387947 | 1.00 | — | — | |
| Butyl Alcohol SCHEMBL27822054 | 0.97 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL28022543 | 0.97 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL27823537 | 0.97 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL28157153 | 0.94 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| 1-Pentanol SCHEMBL6569557 | 0.90 | SMN1; SMN2 (0.75) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL430466 | 0.90 | — | — | |
| Butyl Alcohol SCHEMBL9847540 | 0.90 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL28111680 | 0.90 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039007-A1 | INDOL DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND COMPOSITION FOR THE PREVENTION AND TREATMENT OF METABOLIC DISORDER CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2008-04-03 | — | — | WO | claimed |
| EP-2731710-B1 | METHOD FOR PRODUCING COMPOSITES OUT OF ALUMINIUM OXIDE AND CERIUM/ZIRCONIUM MIXED OXIDES | SASOL GERMANY GMBH (DE) | 2019-09-04 | — | — | EP | disclosed |
| EP-3505241-A1 | METHOD FOR PRODUCING COMPOSITES OUT OF ALUMINIUM OXIDE AND CERIUM/ZIRCONIUM MIXED OXIDES | SASOL Germany GmbH (DE) | 2019-07-03 | — | — | EP | disclosed |
| EP-2545990-B1 | Method for producing composites out of aluminium oxide and cerium/zirconium mixed oxides | SASOL GERMANY GMBH (DE) | 2018-11-28 | — | — | EP | disclosed |
| EP-2731710-A1 | METHOD FOR PRODUCING COMPOSITES FROM ALUMINIUM OXIDE AND CERIUM/ZIRCONIUM MIXED OXIDES | SASOL Germany GmbH (DE) | 2014-05-21 | — | — | EP | disclosed |
| EP-2616072-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2013007242-A1 | METHOD FOR PRODUCING COMPOSITES FROM ALUMINIUM OXIDE AND CERIUM/ZIRCONIUM MIXED OXIDES | SASOL GERMANY GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |
| EP-2545990-A1 | Method for producing composites out of aluminium oxide and cerium/zirconium mixed oxides | SASOL Germany GmbH (DE) | 2013-01-16 | — | — | EP | disclosed |
| WO-2012035039-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011095997-A1 | BENZAMIDE COMPOUNDS AS GLUCOKINASE ACTIVATORS AND THEIR PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-08-11 | — | — | WO | disclosed |
| EP-1385508-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1295123-A1 | SELECTIVE LABELING AND ISOLATION OF PHOSPHOPEPTIDES AND APPLICATIONS TO PROTEOME ANALYSIS | UNIVERSITY OF WASHINGTON (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-1200432-A4 | AMIDO SPIROPIPERIDINES PROMOTE THE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2002076450-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| EP-1200432-A1 | AMIDO SPIROPIPERIDINES PROMOTE THE RELEASE OF GROWTH HORMONE | Merck & Co., Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001096869-A1 | SELECTIVE LABELING AND ISOLATION OF PHOSPHOPEPTIDES AND APPLICATIONS TO PROTEOME ANALYSIS | UNIVERSITY OF WASHINGTON (US) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001004119-A1 | AMIDO SPIROPIPERIDINES PROMOTE THE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 2001-01-18 | — | — | WO | disclosed |
| EP-0699079-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| EP-0687675-A2 | Irreversible HIV protease inhibitors, intermediates, compositions and processes for the preparation thereof | LG Chemical Limited (KR) | 1995-12-20 | — | — | EP | disclosed |
| WO-1995024221-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |