SCHEMBL793520

SCHEMBL793520

CCCCCCCCC(CCCCCC)Cn1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PSEN1 P49768 9/20 0.36
PSEN2 P49810 9/20 0.36
APH1B Q8WW43 9/20 0.36
NCSTN Q92542 9/20 0.36
APH1A Q96BI3 9/20 0.36
PSENEN Q9NZ42 9/20 0.36
OXER1 Q8TDS5 3/20 0.35
GSK3B P49841 2/20 0.33
LMNA P02545 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL793528 1.00 DNM1 (0.37) DNM1MAPTSMN1; SMN2PSEN1PSEN2
SCHEMBL28405960 0.93 DNM1 (0.44) DNM1PSEN1PSEN2APH1BNCSTN
SCHEMBL923650 0.88 DNM1 (0.37) DNM1MAPTSMN1; SMN2
SCHEMBL29394643 0.83 CNR2 (0.44) DNM1MAPTSMN1; SMN2OXER1GSK3B
SCHEMBL28126495 0.82 DNM1 (0.44) DNM1MAPTPSEN1PSEN2APH1B
SCHEMBL6365810 0.82 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL28692216 0.82 DNM1 (0.38) DNM1MAPTSMN1; SMN2LMNA
SCHEMBL22845475 0.81 PSEN1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL17760815 0.80 ALDH1A1 (0.37) DNM1MAPTSMN1; SMN2OXER1
SCHEMBL15206581 0.80 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2435500-B1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2019-10-30 EP disclosed
US-20120142872-A1 PROCESS FOR POLYMERISING (HETERO)AROMATIC COMPOUNDS BASF SE (DE) 2012-06-07 US disclosed
US-20120142872-A1 PROCESS FOR POLYMERISING (HETERO)AROMATIC COMPOUNDS BASF SE (DE) 2012-06-07 US disclosed
US-20120071617-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2012-03-22 US disclosed
US-20120071617-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2012-03-22 US disclosed
WO-2010136353-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2010-12-02 WO disclosed
WO-2010136352-A1 A PROCESS FOR POLYMERISING (HETERO)AROMATIC COMPOUNDS BASF SE (DE) 2010-12-02 WO disclosed
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof SHEFFIELD, THE UNIVERSITY OF (GB) 2005-06-02 US disclosed
EP-1453802-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2004-09-08 EP disclosed
WO-2003050086-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2003-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof CBR3, OR10J3, ORC3 DNM1 2471/4885MAPT 3096/4885SMN1; SMN2 3530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.