Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924284 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 | |
| SCHEMBL7934295 | 0.74 | ALDH1A1 (0.61) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 | |
| SCHEMBL9183045 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 | |
| SCHEMBL8186954 | 0.70 | ALDH1A1 (1.00) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 | |
| SCHEMBL7936744 | 0.70 | ALDH1A1 (0.58) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 | |
| SCHEMBL25211552 | 0.69 | TP53 (0.54) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL29418000 | 0.69 | TP53 (0.54) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL4159127 | 0.68 | ALPL (0.78) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 | |
| SCHEMBL11872723 | 0.68 | ALDH1A1 (0.81) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 | |
| SCHEMBL12225969 | 0.68 | ALDH1A1 (0.54) | ALDH1A1LMNATDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034003-A2 | BENZYLTHIOTETRAZOLE INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-03-25 | — | — | WO | disclosed |