SCHEMBL7935236

SCHEMBL7935236

COCCC(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.54
KMT2A Q03164 2/20 0.52
ALDH1A1 P00352 2/20 0.50
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
UGT1A1 P22309 1/20 0.47
SQLE Q14534 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935232 1.00 ALOX15 (0.54) ALOX15KMT2AALDH1A1MAPTMEN1
SCHEMBL14581768 0.89 ALOX15 (0.65) ALOX15ALDH1A1
SCHEMBL17955374 0.89 ALOX15 (0.65) ALOX15ALDH1A1
SCHEMBL4448966 0.89 ALOX15 (0.65) ALOX15ALDH1A1
SCHEMBL10717973 0.87 ALOX15 (0.41) ALOX15KMT2AALDH1A1MAPT
SCHEMBL10717980 0.87 ALOX15 (0.41) ALOX15KMT2AALDH1A1MAPT
SCHEMBL29500461 0.83 FNTA (0.53) ALOX15
SCHEMBL396770 0.83 FNTA (0.53) ALOX15
SCHEMBL7946220 0.83 ALOX15 (0.82) ALOX15KMT2AALDH1A1
SCHEMBL7946217 0.83 ALOX15 (0.82) ALOX15KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288128-B1 β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound EISAI CO., LTD. (JP) 2001-09-11 US disclosed
US-6111131-A SUCH AS 3,7,11,15,19,23,27,31-OCTAMETHYL-2,6,10,14,18,22,26,30-DOTRIACONTAOCTAEN-1 -OL; USEFUL AS PROPHYLACTIC DRUG FOR IMMUNODEFICIENCY DISEASES AND INFECTIOUS DISEASES EISAI CO., LTD. (JP) 2000-08-29 US disclosed
US-5658958-A β, γ-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals EISAI CO., LTD. (JP) 1997-08-19 US disclosed
US-5280048-A Antiinfection agent EISAI CO., LTD. (JP) 1994-01-18 US disclosed
US-4624966-A β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound EISAI CO., LTD. (JP) 1986-11-25 US disclosed