Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935133 | 1.00 | ALOX15 (0.56) | ALOX15ALOX12KDM4EHIF1AHSD17B10 | |
| SCHEMBL7935135 | 1.00 | ALOX15 (0.56) | ALOX15ALOX12KDM4EHIF1AHSD17B10 | |
| SCHEMBL7938299 | 0.80 | ALOX15 (0.47) | ALOX15ALOX12KDM4EHIF1AHSD17B10 | |
| SCHEMBL7938217 | 0.80 | ALOX15 (0.47) | ALOX15ALOX12KDM4EHIF1AHSD17B10 | |
| SCHEMBL7938214 | 0.80 | ALOX15 (0.47) | ALOX15ALOX12KDM4EHIF1AHSD17B10 | |
| SCHEMBL11042068 | 0.79 | PSMB5 (0.38) | TDP1ALDH1A1LMNAPOLB | |
| SCHEMBL26492419 | 0.78 | ALOX15 (0.61) | ALOX15ALOX12KDM4EHIF1AHSD17B10 | |
| SCHEMBL19354481 | 0.78 | ALOX15 (0.66) | ALOX15ALOX12KDM4EHIF1AHSD17B10 | |
| SCHEMBL7937788 | 0.76 | LDHA (0.58) | ALOX15ALOX12KDM4EKMT2ALMNA | |
| SCHEMBL7937790 | 0.76 | LDHA (0.58) | ALOX15ALOX12KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248573-B1 | SULFONYLATING OR HALOGENATING A (S)-1-PHENYL-2-PROPANOL DERIVATIVE TO PRODUCE (S)-1-PHENYL-2-SUBSTITUTED PROPANE DERIVATIVE; CHEMICAL INTERMEDIATE FOR SYNTHESIS OF ANTIOBESITY DRUG | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0627397-B1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEM (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5508461-A | ANTIOBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0627397-A1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |