Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | INMT | O95050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclocreatine SCHEMBL450343 | 1.00 | CYP2D6 (0.39) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| Cyclocreatine SCHEMBL11796002 | 0.98 | CYP2D6 (0.38) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| Cyclocreatine SCHEMBL1980714 | 0.96 | CYP2D6 (0.37) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| Cyclocreatine SCHEMBL1981687 | 0.91 | INMT (0.40) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL448277 | 0.89 | ACE (0.39) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| Cyclocreatine SCHEMBL936945 | 0.88 | TSHR (0.33) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| Cyclocreatine SCHEMBL1980609 | 0.83 | SMN1; SMN2 (0.44) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL19719147 | 0.82 | — | — | |
| SCHEMBL14537232 | 0.82 | BDKRB2 (0.33) | KMT2ATSHRINMT | |
| Cyclocreatine SCHEMBL9074350 | 0.82 | CRBN (0.35) | CYP2D6CYP2C19POLBCYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242491-B1 | ADMINISTERING CREATINE PHOSPHATE FOR WRINKLE, AGING, AND SOLAR RADIATION RESISTANCE AND AS FREE RADICAL SCAVENGER | LIBRARY PHARMA, INC. | 2001-06-05 | — | — | US | disclosed |