Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465783 | 0.85 | HTR2A (0.35) | HTR2ASIGMAR1 | |
| SCHEMBL1538530 | 0.83 | HTR2A (0.36) | HTR2ASIGMAR1KDM4ELMNATP53 | |
| SCHEMBL3383168 | 0.74 | HTR2A (0.35) | HTR2ASIGMAR1KDM4ELMNATP53 | |
| SCHEMBL8754995 | 0.74 | HTR2A (0.34) | HTR2ASIGMAR1KDM4ELMNATP53 | |
| SCHEMBL818471 | 0.73 | HTR6 (0.33) | HTR2ASIGMAR1KDM4ELMNATP53 | |
| SCHEMBL3383074 | 0.71 | HTR6 (0.33) | HTR2ASIGMAR1 | |
| SCHEMBL8755451 | 0.71 | HTR2A (0.37) | HTR2ASIGMAR1KDM4ELMNATP53 | |
| SCHEMBL7935464 | 0.71 | HTR6 (0.31) | HTR2A | |
| SCHEMBL215792 | 0.71 | HTR2A (0.35) | HTR2A | |
| SCHEMBL7951352 | 0.71 | HTR2A (0.35) | HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0708117-A1 | Process for producing copolymer rubber | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |