Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 10/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16191028 | 0.83 | ACHE (0.38) | KIF11KCNN4PTPN1CYP19A1NR3C1 | |
| SCHEMBL7940700 | 0.82 | KCNN4 (0.48) | KIF11KCNN4PTPN1CYP19A1NFE2L2 | |
| SCHEMBL16191281 | 0.81 | KCNN4 (0.49) | KIF11KCNN4PTPN1CYP19A1NFE2L2 | |
| SCHEMBL7938028 | 0.79 | KCNN4 (0.50) | KIF11KCNN4KCNE1KCNQ1MLNR | |
| SCHEMBL27969252 | 0.79 | KIF11 (0.42) | KIF11KCNN4OPRK1 | |
| SCHEMBL7937247 | 0.78 | KCNN4 (0.39) | KIF11KCNN4KCNE1KCNQ1NFE2L2 | |
| SCHEMBL11865400 | 0.76 | KIF11 (0.41) | KIF11KCNN4KCNE1KCNQ1MLNR | |
| SCHEMBL16191066 | 0.76 | KCNN4 (0.41) | KIF11KCNN4KCNE1KCNQ1MLNR | |
| SCHEMBL11598635 | 0.76 | KCNN4 (0.45) | KIF11KCNN4KCNE1KCNQ1PTPN1 | |
| SCHEMBL7940664 | 0.76 | KIF11 (0.41) | KIF11KCNN4KCNE1KCNQ1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |