Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5846893 | 0.74 | EPAS1 (0.37) | EPAS1 | |
| Hydrochloric Acid SCHEMBL8158204 | 0.73 | EPAS1 (0.36) | EPAS1 | |
| Hydrochloric Acid SCHEMBL5179713 | 0.73 | EPAS1 (0.36) | EPAS1 | |
| Hydrochloric Acid SCHEMBL3181387 | 0.73 | EPAS1 (0.36) | EPAS1 | |
| Hydrochloric Acid SCHEMBL4445844 | 0.73 | EPAS1 (0.36) | EPAS1 | |
| Hydrochloric Acid SCHEMBL4945715 | 0.73 | EPAS1 (0.36) | EPAS1 | |
| SCHEMBL9486149 | 0.71 | EPAS1 (0.47) | EPAS1 | |
| Hydrochloric Acid SCHEMBL5846248 | 0.71 | EPAS1 (0.35) | EPAS1 | |
| Hydrochloric Acid SCHEMBL5845571 | 0.71 | EPAS1 (0.35) | EPAS1 | |
| SCHEMBL5845526 | 0.70 | EPAS1 (0.37) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010012877-A1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | MONTELL TECHNOLOGY COMPANY B.V. | 2001-08-09 | — | — | US | disclosed |
| EP-0702687-A1 | METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montell Technology Company bv (NL) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995027717-A1 | METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY BV (NL) | 1995-10-19 | — | — | WO | disclosed |