Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155771 | 0.76 | EPAS1 (0.36) | EPAS1 | |
| SCHEMBL6703968 | 0.74 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL12822142 | 0.73 | EPAS1 (0.37) | EPAS1 | |
| SCHEMBL5845526 | 0.73 | EPAS1 (0.37) | EPAS1 | |
| Hydrochloric Acid SCHEMBL5846893 | 0.73 | EPAS1 (0.37) | EPAS1 | |
| SCHEMBL4453984 | 0.73 | EPAS1 (0.37) | EPAS1 | |
| SCHEMBL10715546 | 0.73 | EPAS1 (0.35) | EPAS1 | |
| Hydrochloric Acid SCHEMBL7545923 | 0.71 | EPAS1 (0.36) | EPAS1 | |
| Fluoride Ion SCHEMBL8083505 | 0.71 | EPAS1 (0.36) | EPAS1 | |
| SCHEMBL9615109 | 0.71 | EPAS1 (0.36) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569952-A1 | Grinding aid formulations | NORTON COMPANY (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5221295-A | Consists of water insoluble halogenated hydrocarbons or polymers, and polymeric binder curing to a coherent film; abrasive grit | NORTON COMPANY (US) | 1993-06-22 | — | — | US | disclosed |