Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7935816

CCC1=Cc2c(ccc3ccccc23)C1[Hf+2](C1C(CC)=Cc2c1ccc1ccccc21)=[Si](C)C.[Cl-].[Cl-]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
KDM4E B2RXH2 2/20 0.40
SLC6A4 P31645 4/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4464917 0.82 KDM4E (0.37) KDM4ESLC6A4CYP1A2ALDH1A1SLC6A2
Hydrochloric Acid SCHEMBL7938818 0.81 KDM4E (0.38) KDM4EALDH1A1
Hydrochloric Acid SCHEMBL7936805 0.78 KDM4E (0.35) KDM4E
Hydrochloric Acid SCHEMBL7217384 0.77
Hydrochloric Acid SCHEMBL31126393 0.77
Hydrochloric Acid SCHEMBL16393716 0.77
Hydrochloric Acid SCHEMBL2779028 0.76 KDM4E (0.40) KDM4ESLC6A4CYP1A2CYP2C19ALDH1A1
Hydrochloric Acid SCHEMBL5613031 0.76 KDM4E (0.40) KDM4ESLC6A4CYP1A2CYP2C19ALDH1A1
Hydrochloric Acid SCHEMBL7196605 0.76 KDM4E (0.41) KDM4ESLC6A4CYP1A2CYP2C19ALDH1A1
Hydrochloric Acid SCHEMBL3918950 0.74 KDM4E (0.40) KDM4ESLC6A4CYP1A2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed