Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6903687 | 0.87 | SLC6A4 (0.32) | KDM4EALDH1A1SLC6A4DRD2SLC6A2 | |
| Hydrochloric Acid SCHEMBL31126400 | 0.87 | SLC6A4 (0.32) | KDM4EALDH1A1SLC6A4DRD2SLC6A2 | |
| Hydrochloric Acid SCHEMBL4659173 | 0.84 | HSD11B1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL4659079 | 0.82 | HTR1A (0.32) | — | |
| Hydrochloric Acid SCHEMBL4658320 | 0.82 | ALDH1A1 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL338847 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1SLC6A4CYP1A2SLC6A2 | |
| Hydrochloric Acid SCHEMBL7936754 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL4660397 | 0.79 | GSTP1 (0.33) | SLC6A4CYP1A2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL5950985 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7926973 | 0.78 | KDM4E (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2192151-A1 | Nucleated propylene polymer compositions and films therefrom | Idemitsu Kosan Co., Ltd. (JP) | 2010-06-02 | — | — | EP | disclosed |
| US-20090215973-A1 | PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-08-27 | — | — | US | disclosed |
| EP-1865006-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-7544758-B2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| EP-1865007-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-2028198-A1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containinig the same | Idemitsu Kosan Co., Ltd. (JP) | 2009-02-25 | — | — | EP | disclosed |
| EP-2028199-A1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containinig the same | Idemitsu Kosan Co., Ltd. (JP) | 2009-02-25 | — | — | EP | disclosed |
| EP-1873172-A2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | Idemitsu Kosan Co., Ltd. (JP) | 2008-01-02 | — | — | EP | disclosed |
| EP-1867662-A2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | Idemitsu Kosan Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| EP-1867663-A2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | Idemitsu Kosan Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-20060293471-A1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| US-6906155-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20050043495-A1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-6812185-B2 | IMPREGNATION OF A SUPPORT MATERIAL WITH AN IMPREGNATION SOLUTION COMPRISING THE METAL COMPONENT, WHEREIN THE IMPREGNATION SOLUTION FLOWS IN A DIRECTED STREAM THROUGH THE SUPPORT MATERIAL | BASELL POLYOLEFINE GMBH (DE) | 2004-11-02 | — | — | US | disclosed |
| US-20030236164-A1 | Preparation of a metal-containing supported catalyst or a supported catalyst component by impregnation of a support material | EQUISTAR CHEMICALS, LP | 2003-12-25 | — | — | US | disclosed |
| US-6589905-B1 | By impregnating a supporting material with an impregnating solution containing the metal constituent, whereby the impregnating solution flows through the supporting material | BASELL POLYOLEFINE GMBH (DE) | 2003-07-08 | — | — | US | disclosed |
| US-6562886-B1 | A propylene homopolymer or a copolymer of propylene and an alpha -olefin with at least 4 carbon atoms, which is produced through polymerization in the presence of a metallocene catalyst and which has an increased isotactic pentad fraction | IDEMISTSU PETROCHEMICAL CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1095951-A1 | PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-05-02 | — | — | EP | disclosed |
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-1006149-A1 | PROPYLENE POLYMER COMPOSITION AND FILMS MADE THEREFROM | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-06-07 | — | — | EP | disclosed |