Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | PTAFR | P25105 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821626 | 1.00 | SMN1; SMN2 (0.69) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL20067439 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL25609526 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL3677776 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL13854471 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL2927973 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL20067445 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL19821628 | 0.83 | MAPT (0.71) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL30278565 | 0.83 | MAPT (0.71) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL245306 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021009-A2 | STANDARDIZED FUNCTIONAL FOOD PRODUCTS | CURRIER STEPHEN J (US) | 2001-03-29 | — | — | WO | disclosed |