Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.47 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13854471 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2CHRM5CHRM1CHRM3PGR | |
| SCHEMBL26642448 | 0.86 | FABP3 (0.54) | SMN1; SMN2FABP3P2RY10GPR174GPR34 | |
| SCHEMBL14338125 | 0.86 | FABP3 (0.54) | SMN1; SMN2FABP3P2RY10GPR174GPR34 | |
| SCHEMBL13212932 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2FABP3P2RY10GPR174GPR34 | |
| SCHEMBL19821626 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2CHRM5CHRM1CHRM3PGR | |
| SCHEMBL7935832 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2CHRM5CHRM1CHRM3PGR | |
| SCHEMBL26642068 | 0.83 | FABP3 (0.61) | SMN1; SMN2FABP3P2RY10GPR174GPR34 | |
| SCHEMBL26642060 | 0.83 | FABP3 (0.61) | SMN1; SMN2FABP3P2RY10GPR174GPR34 | |
| SCHEMBL14823175 | 0.83 | P2RY10 (0.47) | P2RY10GPR174GPR34LPAR6LPAR1 | |
| SCHEMBL5959434 | 0.83 | FABP3 (0.60) | SMN1; SMN2CHRM5CHRM1CHRM3PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20160024125-A1 | NATURAL LIPIDS CONTAINING NON-OXIDIZABLE FATTY ACIDS | BERGEN TEKNOLOGIOVERFØRING AS (NO) | 2016-01-28 | — | — | US | disclosed |
| US-8343934-B2 | Diverse lead compound autotaxin inhibitors | UNIVERSITY OF MEMPHIS (US) | 2013-01-01 | — | — | US | disclosed |
| US-20120264966-A1 | SULFUR-CONTAINING PHOSPHOLIPID DERIVATIVES | MILLER ANDREW DAVID (GB) | 2012-10-18 | — | — | US | disclosed |
| US-8268891-B1 | Autotaxin inhibitors | UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-8178713-B2 | Sulfur-containing phospholipid derivatives | Pronovo Biopharma Norge AS (NO) | 2012-05-15 | — | — | US | disclosed |
| US-20120100592-A1 | PIPEMIDIC ACID DERIVATIVE AUTOTAXIN INHIBITORS | THE UNIVERSITY OF MEMPHIS | 2012-04-26 | — | — | US | disclosed |
| US-8022239-B2 | Mechanism-based inactivators of autotaxin | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) | 2011-09-20 | — | — | US | disclosed |
| US-20110160148-A1 | Novel Diverse Lead Compound Autotaxin Inhibitors | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) | 2011-06-30 | — | — | US | disclosed |
| US-20100136650-A1 | MECHANISM-BASED INACTIVATORS OF AUTOTAXIN | THE UNIVERSITY OF MEMPHIS | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160148-A1 | Novel Diverse Lead Compound Autotaxin Inhibitors | ENPP2, ABHD16A, PLAAT2 | SMN1; SMN2 2725/4885CHRM5 4060/4885CHRM1 4496/4885 |
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | APOB, APOL1, LDLR | SMN1; SMN2 1150/4885CHRM5 3954/4885CHRM1 4574/4885 |
| US-20120100592-A1 | PIPEMIDIC ACID DERIVATIVE AUTOTAXIN INHIBITORS | ENPP2, PLA2G6, PLA2G10 | SMN1; SMN2 3521/4885CHRM5 2959/4885CHRM1 3149/4885 |
| US-20120264966-A1 | SULFUR-CONTAINING PHOSPHOLIPID DERIVATIVES | SGMS2, SGMS1, PLA2G4C | SMN1; SMN2 4085/4885CHRM5 411/4885CHRM1 710/4885 |
| US-20100136650-A1 | MECHANISM-BASED INACTIVATORS OF AUTOTAXIN | ENPP2, PLA2G12A, PLA2G10 | SMN1; SMN2 3344/4885CHRM5 2266/4885CHRM1 2276/4885 |
| US-20160024125-A1 | NATURAL LIPIDS CONTAINING NON-OXIDIZABLE FATTY ACIDS | FASN, ELOVL1, FADS1 | SMN1; SMN2 4417/4885CHRM5 4725/4885CHRM1 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.