Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971896 | 0.91 | TSHR (0.51) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL11517527 | 0.89 | ALDH1A1 (0.57) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL28682321 | 0.86 | TSHR (0.59) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL1790360 | 0.86 | TSHR (0.65) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL2137984 | 0.85 | TSHR (0.63) | TSHRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL4627588 | 0.85 | ALDH1A1 (0.59) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL28146886 | 0.85 | ALDH1A1 (0.59) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL28134121 | 0.83 | TSHR (0.49) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL560709 | 0.82 | TSHR (0.73) | TSHRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL27839342 | 0.82 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818799-A | COORDINATION CATALYST ALSO COMPRISING AN ALKYL-ALUMINUM-ANTIOXIDENT TO RELEASE THE ANTIOXIDANT IN SITU | SHELL OIL COMPANY (US) | 1989-04-04 | — | — | US | claimed |
| EP-0601496-B2 | Process for the preparation of olefin polymer | MITSUI CHEMICALS INC (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5844046-A | Process for the preparation of olefin polymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0601496-B1 | Process for the preparation of olefin polymer | MITSUI PETROCHEMICAL IND (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0601496-A1 | Process for the preparation of olefin polymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0262790-B1 | TRANSITION METAL CATALYST COMPONENT CONTAINING MAGNESIUM ALKOXY ALKOXIDES | AKZO N.V. (NL) | 1992-08-12 | — | — | EP | disclosed |
| US-4952649-A | COORDINATION CATALYSTS USING BOTH AN ELECTRON DONOR AND ESTERS OF POLYCARBOXYLIC ACIDS; STEREOSPECIFIC; DURABILITY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| EP-0320123-A2 | Process for preparing stabilized olefin polymers | SHELL OIL COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| EP-0262790-A2 | Transition metal catalyst component containing magnesium alkoxy alkoxides | AKZO N.V. (NL) | 1988-04-06 | — | — | EP | disclosed |
| US-4698323-A | Transition metal catalyst component containing magnesium alkoxy alkoxides | STAUFFER CHEMICAL COMPANY (US) | 1987-10-06 | — | — | US | disclosed |