Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 13/20 | 0.56 |
| ▸ | CA12 | O43570 | 12/20 | 0.56 |
| ▸ | CA1 | P00915 | 12/20 | 0.56 |
| ▸ | CA9 | Q16790 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 7/20 | 0.49 |
| ▸ | CA5A | P35218 | 7/20 | 0.49 |
| ▸ | CA7 | P43166 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2215629 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL8579675 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL8028101 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL16731431 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL813505 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL2037245 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL17993795 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL21021147 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL20820941 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL7903998 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730566-B1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| US-5789580-A | Selectively fluorinated organic compounds | BRITISH NUCLEAR FUELS PLC (GB) | 1998-08-04 | — | — | US | disclosed |
| US-4751291-A | Process for the preparation of glycosyl fluorides protected on the oxygen | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-14 | — | — | US | disclosed |
| EP-0231837-A2 | Process for the preparation of water soluble phthalocyanine dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-12 | — | — | EP | disclosed |
| EP-0215376-A2 | Method for the preparation of O-protected glycosyl fluorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-25 | — | — | EP | disclosed |