Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 13/20 | 0.56 |
| ▸ | CA12 | O43570 | 12/20 | 0.56 |
| ▸ | CA1 | P00915 | 12/20 | 0.56 |
| ▸ | CA9 | Q16790 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 7/20 | 0.49 |
| ▸ | CA5A | P35218 | 7/20 | 0.49 |
| ▸ | CA7 | P43166 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935847 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL2215629 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL8579675 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL8028101 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL16731431 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL813505 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL17993795 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL21021147 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL20820941 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL7903998 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232194-A1 | METHODS FOR GLYCOSYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-11-19 | — | — | WO | disclosed |
| EP-2960247-A1 | PHENYL-ALPHA-D-MANNOSIDES FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS CAUSED BY ESCHERICHIA COLI | University of Basel (CH) | 2015-12-30 | — | — | EP | disclosed |
| US-20150175644-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIV BASEL (CH) | 2015-06-25 | — | — | US | disclosed |
| EP-2604619-A2 | Mannose derivatives as antagonists of bacterial adhesion | University of Basel (CH) | 2013-06-19 | — | — | EP | disclosed |
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2012-10-25 | — | — | US | disclosed |
| EP-2513128-A2 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | University of Basel (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073112-A2 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2011-06-23 | — | — | WO | disclosed |
| EP-0912587-B1 | HIGH YIELD STEREOSPECIFIC MANNOSYLATION | TEXAS BIOTECHNOLOGY CORP (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-0912587-A4 | HIGH YIELD STEREOSPECIFIC MANNOSYLATION | TEXAS BIOTECHNOLOGY CORP (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-0730566-B1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| EP-0912587-A1 | HIGH YIELD STEREOSPECIFIC MANNOSYLATION | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5789580-A | Selectively fluorinated organic compounds | BRITISH NUCLEAR FUELS PLC (GB) | 1998-08-04 | — | — | US | disclosed |
| US-5712387-A | High yield stereospecific mannosylation | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| WO-1997044344-A1 | HIGH YIELD STEREOSPECIFIC MANNOSYLATION | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-11-27 | — | — | WO | disclosed |
| EP-0537187-B1 | PROCESS FOR PRODUCING ACYLATED GLYCOSYL FLUORIDES | HOECHST AG (DE) | 1994-09-14 | — | — | EP | disclosed |
| US-5218097-A | PROCESS FOR THE PREPARATION OF PROTECTED MONO-SUGAR AND OLIGO-SUGAR HALIDES | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0373118-A2 | Process for the preparation of glycosyl halides of protected mono- and oligo-saccharides | CIBA-GEIGY AG (CH) | 1990-06-13 | — | — | EP | disclosed |
| EP-0215376-B1 | METHOD FOR THE PREPARATION OF O-PROTECTED GLYCOSYL FLUORIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-24 | — | — | EP | disclosed |
| US-4751291-A | Process for the preparation of glycosyl fluorides protected on the oxygen | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-14 | — | — | US | disclosed |
| EP-0215376-A2 | Method for the preparation of O-protected glycosyl fluorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | MAN2A1, MANBA, M6PR | CYP2D6 2827/4885THRB 1427/4885HSD17B10 3301/4885 |
| US-20150175644-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | MAN2A1, MANBA, M6PR | CYP2D6 2827/4885THRB 1427/4885HSD17B10 3301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.