Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 13/20 | 0.56 |
| ▸ | CA12 | O43570 | 12/20 | 0.56 |
| ▸ | CA1 | P00915 | 12/20 | 0.56 |
| ▸ | CA9 | Q16790 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 7/20 | 0.49 |
| ▸ | CA5A | P35218 | 7/20 | 0.49 |
| ▸ | CA7 | P43166 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935847 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL2215629 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL8579675 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL8028101 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL16731431 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL2037245 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL17993795 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL21021147 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL20820941 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL7903998 | 1.00 | CYP2D6 (0.58) | CYP2D6THRBHSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968751-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7892518-B2 | fluorinating a specific position of a saccharide substrate selectively without affecting a protective group at a temperature within a wide range safely and easily with N, N-diethyl-alpha, alpha-difluoro(3-methyl)benzylamine a fluorinating agent under irradiation with microwave or electromagnetic wave | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-02-22 | — | — | US | disclosed |
| EP-2189467-A2 | Method of fluorination by microwaves | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189466-A2 | METHOD OF FLUORINATION BY MICROWAVES | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-7541341-B2 | Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20080319228-A1 | Method of fluorination | HARA SHOJI | 2008-12-25 | — | — | US | disclosed |
| US-7465712-B2 | Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-12-16 | — | — | US | disclosed |
| US-20080154064-A1 | Method of fluorination | HARA SHOJI | 2008-06-26 | — | — | US | disclosed |
| US-7351863-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-7129381-B2 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-10-31 | — | — | US | disclosed |
| US-5789580-A | Selectively fluorinated organic compounds | BRITISH NUCLEAR FUELS PLC (GB) | 1998-08-04 | — | — | US | disclosed |
| EP-0829104-A1 | HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1998-03-18 | — | — | EP | disclosed |
| EP-0729648-A4 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LTD (AU) | 1997-01-02 | — | — | EP | disclosed |
| EP-0730566-A1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-09-11 | — | — | EP | disclosed |
| EP-0729648-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1996-09-04 | — | — | EP | disclosed |
| WO-1996003357-A1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-02-08 | — | — | WO | disclosed |
| WO-1995012219-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1995-05-04 | — | — | WO | disclosed |
| US-4751291-A | Process for the preparation of glycosyl fluorides protected on the oxygen | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-14 | — | — | US | disclosed |
| US-4749785-A | REACTING PROTECTED HEXOPYRANOSYL FLUORIDE WITH AGLYCON OR SILYL ETHER THEREOF IN PRESENCE OF METAL FLUORIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-07 | — | — | US | disclosed |
| EP-0215376-A2 | Method for the preparation of O-protected glycosyl fluorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154064-A1 | Method of fluorination | FUCA2, FABP2, FGB | CYP2D6 3653/4885THRB 3658/4885HSD17B10 1408/4885 |
| US-20080319228-A1 | Method of fluorination | FUCA2, FABP2, FGB | CYP2D6 3653/4885THRB 3658/4885HSD17B10 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.