Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498341 | 0.74 | HSD17B10 (0.43) | HSD17B10NPSR1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL735831 | 0.72 | HSD17B10 (0.42) | HSD17B10NPSR1TP53GAA | |
| SCHEMBL18258606 | 0.72 | HSD17B10 (0.42) | HSD17B10NPSR1TP53GAA | |
| SCHEMBL28059371 | 0.70 | HSD17B10 (0.41) | HSD17B10NPSR1POLBSMN1; SMN2TDP1 | |
| SCHEMBL11397824 | 0.70 | HSD17B10 (0.41) | HSD17B10NPSR1POLBSMN1; SMN2TDP1 | |
| SCHEMBL27337837 | 0.69 | — | — | |
| SCHEMBL2793671 | 0.67 | NPSR1 (0.57) | HSD17B10NPSR1TSHRMAPK1POLB | |
| SCHEMBL14247750 | 0.67 | RAB9A (0.39) | HSD17B10NPSR1POLBSMN1; SMN2TDP1 | |
| SCHEMBL18258607 | 0.67 | RAB9A (0.39) | HSD17B10NPSR1POLBSMN1; SMN2TDP1 | |
| SCHEMBL14248374 | 0.67 | RAB9A (0.39) | HSD17B10NPSR1POLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884300-B1 | PROCESS FOR PREPARING FREE ALPHA-HYDROXY ACIDS FROM AMMONIUM SALTS THEREOF | NIPPON SODA CO (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-6066763-A | HEATING TO EVOLVE AMMONIA AND WATER, WHICH ARE REMOVED TO LEAVE A LOW MOLECULAR WEIGHT POLY(ALPHA-HYDROXY ACID) RESIDUE; ADDING WATER, HEATING TO HYDROLYZE THE RESIDUE TO FREE ALPHA-HYDROXY ACID; NO BY-PRODUCT DISPOSAL PROBLEMS | NIPPON SODA CO., LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-0884300-A1 | PROCESS FOR PREPARING FREE ALPHA-HYDROXY ACIDS FROM AMMONIUM SALTS THEREOF | NIPPON SODA CO., LTD. (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-4590295-A | Process for the manufacture of p-hydroxyphenyl-acetic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |