Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508846 | 0.76 | PIN1 (0.40) | HSD17B10NPSR1TDP1POLBSMN1; SMN2 | |
| SCHEMBL18258606 | 0.74 | HSD17B10 (0.42) | HSD17B10NPSR1GAA | |
| SCHEMBL735831 | 0.74 | HSD17B10 (0.42) | HSD17B10NPSR1GAA | |
| SCHEMBL7936004 | 0.74 | HSD17B10 (0.42) | HSD17B10NPSR1TDP1POLBSMN1; SMN2 | |
| SCHEMBL11397824 | 0.72 | HSD17B10 (0.41) | HSD17B10NPSR1TDP1POLBSMN1; SMN2 | |
| SCHEMBL28059371 | 0.72 | HSD17B10 (0.41) | HSD17B10NPSR1TDP1POLBSMN1; SMN2 | |
| SCHEMBL14247750 | 0.69 | RAB9A (0.39) | HSD17B10NPSR1TDP1POLBSMN1; SMN2 | |
| SCHEMBL2793671 | 0.69 | NPSR1 (0.57) | HSD17B10NPSR1POLBHPGDHTT | |
| SCHEMBL14248374 | 0.69 | RAB9A (0.39) | HSD17B10NPSR1TDP1POLBSMN1; SMN2 | |
| SCHEMBL18258607 | 0.69 | RAB9A (0.39) | HSD17B10NPSR1TDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058300-B1 | SUCCINIC ACID DIESTER DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND USE OF THE DERIVATIVE IN THE PRODUCTION OF PHARMACEUTICAL PREPARATION | DAINIPPON SUMITOMO PHARMA CO (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-8106230-B2 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-8030486-B2 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20110046373-A1 | SUCCINIC ACID DIESTER DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND USE OF THE DERIVATIVE IN THE PRODUCTION OF PHARMACEUTICAL PREPARATION | INAGAKI TAKASHI | 2011-02-24 | — | — | US | disclosed |
| US-20100076203-A1 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | DAINIPPON SUMITOMO PHARMA CO., LTD. | 2010-03-25 | — | — | US | disclosed |
| EP-2058300-A1 | SUCCINIC ACID DIESTER DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND USE OF THE DERIVATIVE IN THE PRODUCTION OF PHARMACEUTICAL PREPARATION | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-0520320-B1 | Tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3'-pyrrolidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0520320-A2 | Tetrahydropyrrolo 1,2-a pyrazine-4-spiro-3'-pyrrolidine derivatives, processes for the preparation thereof and pharaceutical compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-12-30 | — | — | EP | disclosed |
| US-4421914-A | IMMUNE FUNCTION REGULATORS | TEIJIN LIMITED (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0049902-A2 | Novel thiazolo(3,2-a)pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1982-04-21 | — | — | EP | disclosed |
| US-4148998-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1979-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046373-A1 | SUCCINIC ACID DIESTER DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND USE OF THE DERIVATIVE IN THE PRODUCTION OF PHARMACEUTICAL PREPARATION | SUCNR1, DLST, SHMT2 | HSD17B10 257/4885NPSR1 2027/4885TDP1 4164/4885 |
| US-20100076203-A1 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | SUCNR1, DLST, SHMT2 | HSD17B10 257/4885NPSR1 2027/4885TDP1 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.