Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943712 | 1.00 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL12232762 | 1.00 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL7947115 | 1.00 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL7943705 | 0.98 | NAAA (0.54) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL6058509 | 0.91 | ALDH1A1 (0.56) | NAAAEPHX1TSHRHCAR2ALDH1A1 | |
| SCHEMBL14566016 | 0.90 | NAAA (0.52) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL9153319 | 0.90 | NAAA (0.52) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL10515804 | 0.90 | NAAA (0.52) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL28947501 | 0.88 | NAAA (0.48) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL12749791 | 0.88 | TSHR (0.48) | NAAAEPHX1TSHRHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193992-C | Synthesis of 3,6-dialkyl 5,6-dihydro-4-hydroxide-2H-pyran-2-ketone | HOFFMANN LA ROCHE (CH) | 2005-03-23 | — | — | CN | disclosed |
| US-6331620-B1 | AS POLYMERIZATION CATALYSTS FOR PRODUCING STEREOSPECIFIC HOMOPOLYMER OR COPOLYMER OF ALPHA-OLEFINS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-12-18 | — | — | US | disclosed |