Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926246 | 0.92 | GHSR (0.37) | GHSRPPIA | |
| SCHEMBL7935099 | 0.86 | GHSR (0.33) | GHSRPPIAMEN1MAPK1KMT2A | |
| SCHEMBL2745084 | 0.82 | GHSR (0.38) | GHSRMAPTPPIAMEN1MAPK1 | |
| SCHEMBL1820679 | 0.82 | MAPT (0.39) | GHSRMAPTPPIAMEN1MAPK1 | |
| SCHEMBL4094284 | 0.79 | MAPT (0.44) | GHSRMAPTPPIAMEN1MAPK1 | |
| SCHEMBL1350921 | 0.79 | MAPT (0.47) | GHSRMAPTPPIAMEN1MAPK1 | |
| SCHEMBL7934956 | 0.78 | GHSR (0.36) | GHSRKMT2AALDH1A1 | |
| SCHEMBL1353132 | 0.77 | MAPT (0.50) | GHSRMAPTPPIAMEN1MAPK1 | |
| SCHEMBL978565 | 0.77 | MAPT (0.50) | GHSRMAPTPPIAMEN1MAPK1 | |
| SCHEMBL8859492 | 0.77 | GHSR (0.39) | GHSRMAPTPPIAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862464-A4 | AMINO ACID ANALOGS FOR TUMOR IMAGING | UNIV EMORY (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-0862464-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |