SCHEMBL978565

SCHEMBL978565

COC(=O)C1(NC(=O)OC(C)(C)C)CCCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
ALDH1A1 P00352 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
FAAH O00519 3/20 0.35
CA12 O43570 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA2 P00918 1/20 0.35
EPHX1 P07099 1/20 0.35
PPIA P62937 2/20 0.34
P2RX7 Q99572 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
GHSR Q92847 1/20 0.33
DGAT1 O75907 1/20 0.33
BTK Q06187 1/20 0.33
CTSL P07711 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1353132 1.00 MAPT (0.50) MAPTALDH1A1L3MBTL1NPSR1MEN1
SCHEMBL1350921 0.98 MAPT (0.47) MAPTALDH1A1L3MBTL1NPSR1MEN1
SCHEMBL4094284 0.95 MAPT (0.44) MAPTALDH1A1L3MBTL1NPSR1MEN1
SCHEMBL1820679 0.91 MAPT (0.39) MAPTALDH1A1L3MBTL1NPSR1MEN1
SCHEMBL27646197 0.86 GAA (0.37) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL5427902 0.85 MAPT (0.37) MAPTALDH1A1L3MBTL1NPSR1MEN1
SCHEMBL5197158 0.85 MAPT (0.39) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL18482797 0.85 MAPT (0.36) MAPTALDH1A1L3MBTL1NPSR1MEN1
SCHEMBL15116645 0.84 GAA (0.36) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL1012064 0.84 FAAH (0.39) MAPTMEN1KMT2AGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626888-A1 COMPOUNDS Redx Pharma Limited (GB) 2025-10-08 EP disclosed
WO-2024115890-A1 COMPOUNDS REDX PHARMA PLC (GB) 2024-06-06 WO disclosed
EP-2120965-B1 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES NOVABAY PHARMACEUTICALS INC (US) 2014-11-05 EP disclosed
US-8765759-B2 Monocyclic CGRP receptor antagonists MERCK SHARP & DOHME CORP. (US) 2014-07-01 US disclosed
EP-2271346-B1 MONOCYCLIC CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME (US) 2014-01-01 EP disclosed
US-8415497-B2 N-halogenated amino compounds and derivatives NOVABAY PHARMACEUTICALS, INC. (US) 2013-04-09 US disclosed
US-8415497-B2 N-halogenated amino compounds and derivatives NOVABAY PHARMACEUTICALS, INC. (US) 2013-04-09 US disclosed
US-8415497-B2 N-halogenated amino compounds and derivatives NOVABAY PHARMACEUTICALS, INC. (US) 2013-04-09 US disclosed
US-20110021516-A1 MONOCYCLIC CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME CORP (US) 2011-01-27 US disclosed
US-20100311791-A1 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES NOVABAY PHARMACEUTICALS, INC. 2010-12-09 US disclosed
US-20100311791-A1 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES NOVABAY PHARMACEUTICALS, INC. 2010-12-09 US disclosed
US-20100311791-A1 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES NOVABAY PHARMACEUTICALS, INC. 2010-12-09 US disclosed
WO-2008083347-A1 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES NOVABAY PHARMACEUTICALS, INC. (US) 2008-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021516-A1 MONOCYCLIC CGRP RECEPTOR ANTAGONISTS CCKAR, CALCRL, CCKBR MAPT 2813/4885ALDH1A1 2157/4885L3MBTL1 4300/4885
US-20100311791-A1 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES DCTD, DDC, DAO MAPT 3452/4885ALDH1A1 3847/4885L3MBTL1 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.