SCHEMBL7936591

SCHEMBL7936591

C=CCc1cc(OC(=O)C=C)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.37
RAB9A P51151 5/20 0.37
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
POLB P06746 2/20 0.36
PDE6D O43924 1/20 0.36
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
IGF2BP2 Q9Y6M1 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PKM P14618 1/20 0.33
THRB P10828 3/20 0.32
THRA P10827 1/20 0.32
GABRA1 P14867 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29153163 0.83 NPC1 (0.42) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL2780353 0.82 NPC1 (0.45) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL5241058 0.81 NPC1 (0.39) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL712510 0.79 NPC1 (0.43) NPC1RAB9AALDH1A1KDM4EMAPT
SCHEMBL299318 0.78 NPC1 (0.51) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29566424 0.78 NPC1 (0.51) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29384819 0.78 NPC1 (0.58) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL285279 0.78 NPC1 (0.58) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL28234016 0.76 NPC1 (0.40) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL28214707 0.75 PDE6D (0.39) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112310-A1 UV STABILIZED ETHYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-07-04 EP claimed
US-6147170-A UV stabilized ethylene copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-11-14 US claimed
WO-2000009602-A1 UV STABILIZED ETHYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-02-24 WO claimed
EP-2346840-B1 UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS NOVARTIS AG (CH) 2013-12-25 EP disclosed
EP-1112310-A1 UV STABILIZED ETHYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-07-04 EP disclosed
US-6147170-A UV stabilized ethylene copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-11-14 US disclosed
WO-2000009602-A1 UV STABILIZED ETHYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-02-24 WO disclosed
EP-0896968-A1 MODIFIED COPOLYMER, PROCESS FOR PREPARING THE SAME, AND CURABLE RESIN COMPOSITION DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-02-17 EP disclosed
EP-0577122-B1 Photographic elements incorporating polymeric ultraviolet absorbers EASTMAN KODAK CO (US) 1996-03-13 EP disclosed
US-5384235-A Photographic elements incorporating polymeric ultraviolet absorbers EASTMAN KODAK COMPANY (US) 1995-01-24 US disclosed
EP-0577122-A1 Photographic elements incorporating polymeric ultraviolet absorbers EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
EP-0131468-B1 ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES IOLAB CORPORATION (US) 1990-01-17 EP disclosed
EP-0131468-B1 ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES IOLAB CORPORATION (US) 1990-01-17 EP disclosed
US-4528311-A Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxyphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-07-09 US disclosed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP disclosed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP disclosed