Sugi Predict

Sugi Predict / Compounds / SCHEMBL299318

SCHEMBL299318

SCHEMBL299318

C=CC(=O)Oc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 7/20 0.51
▸ RAB9A P51151 7/20 0.51
▸ LMNA P02545 1/20 0.51
▸ IGF2BP2 Q9Y6M1 1/20 0.42
▸ ALDH1A1 P00352 4/20 0.41
▸ SMN1; SMN2 Q16637 4/20 0.41
▸ PDE6D O43924 1/20 0.40
▸ MAPT P10636 5/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ THRB P10828 4/20 0.35
▸ POLB P06746 3/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29566424 1.00 NPC1 (0.51) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL7921927 0.94 NPC1 (0.46) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL7160226 0.90 NPC1 (0.49) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL16581362 0.89 NPC1 (0.41) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL29384531 0.89 NPC1 (0.41) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL29315721 0.87 NPC1 (0.42) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL29315723 0.85 NPC1 (0.41) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL29315727 0.84 NPC1 (0.40) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL29315728 0.84 NPC1 (0.40) NPC1RAB9ALMNAIGF2BP2ALDH1A1
SCHEMBL4189444 0.84 THRB (0.53) NPC1RAB9ALMNAIGF2BP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1020 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 — — US claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 — — US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 — — US claimed
US-20250052927-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-13 — — US claimed
US-20240392055-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-11-28 — — US claimed
US-20240383865-A1 HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS ALCON INC (CH) 2024-11-21 — — US claimed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 — — US claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 — — US claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 — — WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 — — US claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 — — US claimed
WO-2010133680-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2010-11-25 — — WO claimed
WO-2006113164-A1 UV-ABSORBING LAYER FOR POLARIZER PLATE NITTO DENKO CORPORATION (JP) 2006-10-26 — — WO claimed
US-20060234035-A1 Protective cover sheet comprising a UV-absorbing layer for a polarizer plate and method of making the same EASTMAN KODAK COMPANY 2006-10-19 — — US claimed
EP-1153076-A4 POLYMER LATEX FOR UV ABSORPTION ON DIFFERENT SUBSTRATES MILLIKEN RES CORP (US) 2004-12-15 — — EP claimed
US-6482757-B2 FABRIC SUBSTRATE MILLIKEN & COMPANY 2002-11-19 — — US claimed
EP-1153076-A1 POLYMER LATEX FOR UV ABSORPTION ON DIFFERENT SUBSTRATES MILLIKEN RESEARCH CORPORATION (US) 2001-11-14 — — EP claimed
US-20010012743-A1 Polymer latex for ultraviolet absorption on different substrates VOGT KIRKLAND W (US) 2001-08-09 — — US claimed
US-6194330-B1 EMULSION POLYMERIZATION OF A BENZOTRIAZOLE- OR BENZOPHENONE-CONTAINING MONOMER WITH A VINYL FUNCTIONAL MONOMER IN THE PRESENCE OF A CHAIN TRANSFER AGENT, PREFERABLY 1-DODECANETHIOL MILLIKEN & COMPANY 2001-02-27 — — US claimed
WO-2000006643-A1 POLYMER LATEX FOR UV ABSORPTION ON DIFFERENT SUBSTRATES MILLIKEN RESEARCH CORPORATION (US) 2000-02-10 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 NPC1 3917/4885RAB9A 2881/4885LMNA 1029/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L NPC1 3998/4885RAB9A 4835/4885LMNA 2948/4885
US-20240383865-A1 HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS VCL, HBS1L, SAAL1 NPC1 4212/4885RAB9A 4844/4885LMNA 2529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.