Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934469 | 0.83 | POLB (0.77) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL14202808 | 0.80 | POLB (0.69) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL5100999 | 0.80 | MEN1 (0.57) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL7931737 | 0.79 | HPGD (0.60) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL19575701 | 0.79 | NPC1 (0.52) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL9210058 | 0.77 | HDAC1 (0.58) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL7932534 | 0.77 | CA1 (0.50) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL12354957 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL7931375 | 0.76 | KMT2A (0.80) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL7934018 | 0.75 | POLB (0.47) | MEN1KMT2APOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033360-A1 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT | 1/3 ABSOLUTE SCIENCE, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2009045761-A1 | COMPOUNDS AND METHODS FOR TREATING ZINC MATRIX METALLOPROTEASE DEPENDENT DISEASES | ABSOLUTE SCIENCE, INC. (US) | 2009-04-09 | — | — | WO | disclosed |