Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CD74 | P04233 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743172 | 0.81 | CALM1 (0.41) | CALM1FEN1BRD4TAAR1ALDH1A1 | |
| SCHEMBL1723556 | 0.78 | TAAR1 (0.48) | CALM1TAAR1ALDH1A1HRH3GAA | |
| SCHEMBL4081720 | 0.78 | TAAR1 (0.41) | CALM1FEN1BRD4TAAR1ALDH1A1 | |
| SCHEMBL82538 | 0.77 | TAAR1 (0.43) | CALM1BRD4TAAR1ALDH1A1HRH3 | |
| SCHEMBL6626882 | 0.77 | CALM1 (0.41) | CALM1BRD4TAAR1ALDH1A1HRH3 | |
| SCHEMBL4734293 | 0.77 | CALM1 (0.41) | CALM1BRD4TAAR1ALDH1A1HRH3 | |
| SCHEMBL16877215 | 0.77 | CALM1 (0.41) | CALM1BRD4TAAR1ALDH1A1HRH3 | |
| SCHEMBL13604219 | 0.77 | LTB4R (0.49) | CALM1TAAR1ALDH1A1HRH3MEN1 | |
| SCHEMBL949037 | 0.77 | BRD4 (0.43) | CALM1FEN1BRD4GAATSHR | |
| SCHEMBL5801624 | 0.76 | POLB (0.46) | CALM1BRD4TAAR1ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |