Sugi Predict

Sugi Predict / Compounds / Methane

Methane

Methane

SCHEMBL7936819

C.CCc1ccc2cc3ccccc3c(O)c2c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.53
▸ CYP2A6 P11509 1/20 0.53
▸ MEN1 O00255 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ PTPN22 Q9Y2R2 1/20 0.41
▸ TRPA1 O75762 1/20 0.41
▸ KIF11 P52732 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27480938 0.98 CYP1A2 (0.55) CYP1A2CYP2A6MEN1POLBKMT2A
Propane SCHEMBL243407 0.83 PTPN22 (0.50) CYP1A2MEN1POLBKMT2APTPN22
SCHEMBL28851361 0.82 CYP1A2 (0.47) CYP1A2
SCHEMBL29566210 0.80 KIF11 (0.52) CYP1A2CYP2A6POLBTRPA1KIF11
SCHEMBL1043776 0.80 KIF11 (0.52) CYP1A2CYP2A6POLBTRPA1KIF11
Butane SCHEMBL241215 0.79 PTPN22 (0.46) CYP1A2MEN1POLBKMT2APTPN22
Methane SCHEMBL155047 0.79 PTPN22 (0.54) CYP1A2MEN1KMT2APTPN22
Methane SCHEMBL2327641 0.79 PTPN22 (0.54) CYP1A2MEN1KMT2APTPN22
SCHEMBL29510037 0.78 KIF11 (0.50) CYP1A2CYP2A6MEN1POLBKMT2A
SCHEMBL22092122 0.78 KIF11 (0.50) CYP1A2CYP2A6POLBTRPA1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242161-B1 ABSORPTION COATINGS USING COPOLYMERS JSR CORPORATION (JP) 2001-06-05 — — US disclosed