SCHEMBL7936989

SCHEMBL7936989

NC(=O)Cc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
CA2 P00918 1/20 0.55
SRD5A2 P31213 3/20 0.55
ATM Q13315 2/20 0.50
PLA2G10 O15496 1/20 0.50
PLA2G2A P14555 1/20 0.50
VNN1 O95497 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28093413 0.92 CA2 (0.64) ALDH1A1CA2SRD5A2LMNA
SCHEMBL11137347 0.84 CA2 (0.55) CA2SRD5A2
SCHEMBL1415906 0.83 SRD5A2 (0.73) ALDH1A1CA2SRD5A2ATMTDP1
SCHEMBL25676 0.83 CES1 (0.64) ALDH1A1CA2PLA2G10PLA2G2AL3MBTL1
SCHEMBL29163965 0.82 SRD5A2 (0.79) ALDH1A1SRD5A2ATMTDP1L3MBTL1
Methane SCHEMBL11705397 0.82 SRD5A2 (0.71) ALDH1A1CA2SRD5A2ATMTDP1
SCHEMBL3690716 0.81 CA2 (0.61) ALDH1A1CA2SRD5A2
Methane SCHEMBL2335788 0.81 CES1 (0.61) ALDH1A1CA2PLA2G10PLA2G2AL3MBTL1
SCHEMBL4165526 0.81 CES1 (0.61) ALDH1A1CA2PLA2G10PLA2G2AL3MBTL1
Hydrochloric Acid SCHEMBL1621316 0.81 CES1 (0.61) ALDH1A1CA2PLA2G10PLA2G2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105777609-A Preparation method of 7-benzoyl-1, 3-indoline-2-ketone 南京工业大学 2016-07-20 CN disclosed
CN-102438979-A Novel crystal of benzoylphenylacetamide derivative MEDICHEM SA 2012-05-02 CN disclosed
US-6245817-B1 NEUROPEPTIDE Y BAYER CORPORATION 2001-06-12 US disclosed